ENZYMOLOGICAL INDICATORS OF BLOOD INDIVIDUALS WITHTUBERCULOSIS DISEASE

Abstract

The article presents the results of the study of the main enzymological
indicators of blood of people with tuberculosis. The study was conducted on the
basis of the Kherson Regional TB Dispensary. Ten patients aged 47 to 57 years
old who were diagnosed with pulmonary tuberculosis were examined.
Among the examined patients, there were 5 non-tuberculous women and 5
men. They underwent a course of chemotherapeutic treatment at the offices of the
Kherson Regional TB Dispensary. According to doctors, all patients had the first
diagnosis of pulmonary tuberculosis.
The study of biochemical parameters in patients was performed using several
methods, such as the Wrightman-Frenkel method for the determination of alanine
aminotransferase and aspartate aminotransferase, the Endrasic method for
determining bilirubin and the Huerho-Popper method (thymol test) to determine
the change in the ratio of protein fractions in serum. Measurements were carried
out on a semi-automatic biochemical analyzer BiochemSAPlus (HTI Medica,
USA). In males and females there is an increase in enzymes alanine
aminotransferase, aspartate aminotransferase. This indicates damage to
hepatocytes, an increase in the activity of transferees within double the norm,
indicates a detailed picture of parenchymal hepatitis.
Key words: alanine aminotransferase, aspartate aminotransferase, bilirubin,
tuberculosis.